Goal

• To improve long-term stabilisation of orthopaedic implants

Concept

• Coating technology that allows coating of implants with bisphosphonates
• Leading to significantly improved long-term stabilisation of implants as bisphosphonates block osteoclastic activity

Technology

• Simply and easy-to-use coating process
• Allowing deposition of bisphosphonates on all implant surfaces
• Technology platform can be used as a drug delivery system

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USP

• Platform technology without any change of original implants
• One-phase system: carrier = drug
• No linker, no toxic side effects
• Release can be adjusted
• Independent of the substrate material
• Gamma & EtO sterilisable
• Low-cost technology

Schematic diagram of Nexilis propietary one phase system coating